USP22 Antibody

Size

100ug

Clone Number

Aliases

Deubiquitinating enzyme 22 antibody; KIAA1063 antibody; Ubiquitin carboxyl terminal hydrolase 22 antibody; Ubiquitin carboxyl-terminal hydrolase 22 antibody; Ubiquitin specific peptidase 22 antibody; Ubiquitin specific peptidase 3 like antibody; Ubiquitin specific processing protease 22 antibody; Ubiquitin specific protease 22 antibody; Ubiquitin thioesterase 22 antibody; Ubiquitin thiolesterase 22 antibody; Ubiquitin-specific-processing protease 22 antibody; UBP22_HUMAN antibody; USP 22 antibody; Usp22 antibody; USP3L antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UPT9

Immunogen

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 22 protein (330-478AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

USP22

Research Areas

Epigenetics and Nuclear Signaling; Cell biology