UHRF2 Antibody

Size

100ug

Clone Number

Aliases

DKFZp434B0920 antibody; DKFZp686G0837 antibody; E3 ubiquitin-protein ligase UHRF2 antibody; MGC33463 antibody; Np95 like RING finger protein antibody; Np95-like ring finger protein antibody; Np95/ICBP90 like RING finger protein antibody; Np95/ICBP90-like RING finger protein antibody; Nuclear protein 97 antibody; Nuclear zinc finger protein Np97 antibody; RING finger protein 107 antibody; RNF 107 antibody; RP11-472F14.2 antibody; Ubiquitin like containing PHD and RING finger domains protein 2 antibody; Ubiquitin-like PHD and RING finger domain-containing protein 2 antibody; Ubiquitin-like-containing PHD and RING finger domains protein 2 antibody; Uhrf2 antibody; UHRF2_HUMAN antibody; URF 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96PU4

Immunogen

Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UHRF2

Research Areas

Cell biology