UGT1A9 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a UDP-glucuronosyltransferase| an enzyme of the glucuronidation pathway that transforms small lipophilic molecules| such as steroids| bilirubin| hormones| and drugs| into water-soluble| excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons| resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site| and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human UGT1A9

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

UGT1A9; UDP-glucuronosyltransferase 1-9; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; EC 2.4.1.17; UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; UDP-glucuronosyltransferase 1A9; lugP4