UGT1A1 Antibody

Size

100ug

Clone Number

Aliases

BILIQTL1 antibody; Bilirubin specific UDPGT isozyme 1 antibody; bilirubin UDP glucuronosyltransferase 1 1 antibody; bilirubin UDP glucuronosyltransferase isozyme 1 antibody; Bilirubin-specific UDPGT isozyme 1 antibody; EC 2.4.1.17 antibody; GNT1 antibody; HUG BR1 antibody; HUG-BR1 antibody; HUGBR1 antibody; PHENOL/BILIRUBIN UDP GLUCURONOSYLTRANSFERASE antibody; UD11_HUMAN antibody; UDP glucuronosyltransferase 1 1 [Precursor] antibody; UDP glucuronosyltransferase 1 family polypeptide A1 antibody; UDP glucuronosyltransferase 1A1 antibody; UDP GLYCOSYLTRANSFERASE 1 antibody; UDP-glucuronosyltransferase 1-1 antibody; UDP-glucuronosyltransferase 1-A antibody; UDP-glucuronosyltransferase 1A1 antibody; UDPGT antibody; UDPGT 1-1 antibody; UGT 1A antibody; UGT-1A antibody; UGT1 antibody; UGT1 01 antibody; UGT1*1 antibody; UGT1-01 antibody; UGT1.1 antibody; UGT1A antibody; Ugt1a1 antibody; URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE, BILIRUBIN/PHENOL antibody; URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 antibody; URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P22309

Immunogen

Recombinant Human UDP-glucuronosyltransferase 1-1 protein (395-482AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UGT1A1

Research Areas

Metabolism