UFM1 Antibody

Size

100ug

Clone Number

Aliases

BM 002 antibody; BM002 antibody; C13orf20 antibody; Chromosome 13 open reading frame 20 antibody; Ubiquitin fold modifier 1 antibody; Ubiquitin-fold modifier 1 antibody; UFM1 antibody; UFM1_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P61960

Immunogen

Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UFM1

Research Areas

Others