UBIAD1 Antibody

Size

100ug

Clone Number

Aliases

RP4-796F18.1 antibody; SCCD antibody; TERE 1 antibody; tere1 antibody; Transitional epithelia response protein antibody; Transitional epithelial response protein 1 antibody; UbiA prenyltransferase domain containing 1 antibody; UbiA prenyltransferase domain containing protein 1 antibody; UbiA prenyltransferase domain-containing protein 1 antibody; UBIA1_HUMAN antibody; UBIAD 1 antibody; Ubiad1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5Z9

Immunogen

Recombinant Human UbiA prenyltransferase domain-containing protein 1 protein (1-82AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UBIAD1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Tags & Cell Markers