UBE4A Polyclonal Antibody

Ab type

Primary antibody

Background

UBE4A encodes a member of the U-box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human UBE4A.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

122561

synonyms

UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A