UBE3C Antibody

Size

100ug

Clone Number

Aliases

HectH2 antibody; KIAA0010 antibody; KIAA10 antibody; Ube3c antibody; UBE3C_HUMAN antibody; Ubiquitin protein isopeptide ligase (E3) antibody; Ubiquitin protein ligase E3C antibody; Ubiquitin-protein ligase E3C antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15386

Immunogen

Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either \'Lys-29\'- or \'Lys-48\'-linked polyubiquitin chains. Has preference for \'Lys-48\' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UBE3C

Research Areas

Cell biology