UBE2T Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

Cell proliferation inducing gene 50 protein antibody; Cell proliferation-inducing gene 50 protein antibody; HSPC150 antibody; HSPC150 protein similar to ubiquitin conjugating enzyme antibody; PIG50 antibody; Ube2t antibody; UBE2T_HUMAN antibody; Ubiquitin carrier protein T antibody; Ubiquitin conjugating enzyme antibody; ubiquitin conjugating enzyme E2 T antibody; Ubiquitin conjugating enzyme E2T antibody; Ubiquitin protein ligase T antibody; Ubiquitin-conjugating enzyme E2 T antibody; Ubiquitin-protein ligase T antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NPD8

Immunogen

Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer \'Lys-11\'-, \'Lys-27\'-, \'Lys-48\'- and \'Lys-63\'-linked polyubiquitination.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UBE2T

Research Areas

Epigenetics and Nuclear Signaling; Cell biology