UBE2M Antibody

Size

100ul

Clone Number

Aliases

hUbc12 antibody; NEDD8 carrier protein antibody; NEDD8 conjugating enzyme Ubc12 antibody; NEDD8 protein ligase antibody; NEDD8-conjugating enzyme Ubc12 antibody; UBC-RS2 antibody; UBC12 antibody; UBC12_HUMAN antibody; ube2m antibody; ubiquitin carrier protein M antibody; Ubiquitin conjugating enzyme E2 M antibody; Ubiquitin-conjugating enzyme E2 M antibody; ubiquitin-protein ligase M antibody; yeast UBC12 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P61081

Immunogen

Peptide sequence from Human NEDD8-conjugating enzyme Ubc12 protein (11-28AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UBE2M

Research Areas

Epigenetics and Nuclear Signaling; Cell biology