UBE2K Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Ubiquitin-conjugating enzyme E2 K ;EC 6.3.2.19;Huntingtin-interacting protein 2;HIP-2;Ubiquitin carrier protein;Ubiquitin-conjugating enzyme E2-25 kDa;Ubiquitin-conjugating enzyme E2;25K;