UBE2D2 Antibody

Size

100ug

Clone Number

Aliases

E2(17)KB2 antibody; OTTHUMP00000223475 antibody; OTTHUMP00000223476 antibody; OTTHUMP00000223477 antibody; OTTHUMP00000223478 antibody; OTTHUMP00000224375 antibody; PUBC 1 antibody; PUBC1 antibody; UB2D2_HUMAN antibody; UBC 4 antibody; UBC 4/5 antibody; UBC4 antibody; UBC4/5 antibody; UBC4/5 homolog yeast antibody; UBCH 5B antibody; UBCH5B antibody; UBE2D2 antibody; Ubiquitin carrier protein antibody; Ubiquitin carrier protein D2 antibody; Ubiquitin conjugating enzyme E2 17 kDa 2 antibody; Ubiquitin conjugating enzyme E2 D2 antibody; Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5) antibody; Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast) antibody; Ubiquitin conjugating enzyme E2D 2 antibody; Ubiquitin protein ligase D2 antibody; Ubiquitin-conjugating enzyme E2 D2 antibody; Ubiquitin-conjugating enzyme E2(17)KB 2 antibody; Ubiquitin-conjugating enzyme E2-17 kDa 2 antibody; Ubiquitin-protein ligase D2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P62837

Immunogen

Recombinant Human Ubiquitin-conjugating enzyme E2 D2 protein (1-147AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \\\'Lys-48\\\'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

UBE2D2

Research Areas

Epigenetics and Nuclear Signaling; Cell biology