ABCbiolab
SKU:ABCB15484
UB2R2 Polyclonal Antibody
UB2R2 Polyclonal Antibody
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Ab type
Primary antibody
Background
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
Reactivity
Human, Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from part region of human protein
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
synonyms
Ubiquitin-conjugating enzyme E2 R2 ;EC 6.3.2.19;Ubiquitin carrier protein R2;Ubiquitin-conjugating enzyme E2-CDC34B;Ubiquitin-protein ligase R2
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