U2AF1L4 Antibody

Size

100ul

Clone Number

Aliases

FLJ35525 antibody; MGC33901 antibody; Splicing factor U2AF 26 kDa subunit antibody; U2 auxiliary factor 26 antibody; U2 small nuclear RNA auxiliary factor 1 like 3 antibody; U2 small nuclear RNA auxiliary factor 1 like 4 antibody; U2 small nuclear RNA auxiliary factor 1 like protein 3 antibody; U2 small nuclear RNA auxiliary factor 1 like protein 4 antibody; U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody; U2 small nuclear RNA auxiliary factor 1-like protein 4 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1 like 3 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 antibody; U2AF1 like protein 3 antibody; U2AF1 RS3 antibody; U2AF1-like protein 3 antibody; U2AF1L3V1 antibody; U2AF1L4 antibody; U2AF1RS3 antibody; U2af26 antibody; U2AF4_HUMAN antibody; U2RNU2 small nuclear RNA auxiliary factor 1 like 3 antibody; U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WU68

Immunogen

Recombinant Human Splicing factor U2AF 26 kDa subunit protein (1-202AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3\\\'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3\\\'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

U2AF1L4

Research Areas

Epigenetics and Nuclear Signaling