TYW5 Antibody

Size

100ug

Clone Number

Aliases

TYW5 antibody; C2orf60 antibody; tRNA wybutosine-synthesizing protein 5 antibody; hTYW5 antibody; EC 1.14.11.42 antibody; tRNA(Phe antibody; 7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

A2RUC4

Immunogen

Recombinant Human tRNA wybutosine-synthesizing protein 5 protein (1-152AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3\\\'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TYW5

Research Areas

Cell biology