Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such| it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

130570

synonyms

Tyk 2 ;Phospho Tyr292; Non-receptor tyrosine-protein kinase TYK2; EC 2.7.10.2