Tuberin Polyclonal Antibody

Ab type

Primary antibody

Background

Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Tuberin. AA range:947-996

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

200749

synonyms

TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein