Tuberin(Phospho Thr1462) Polyclonal Antibody

Ab type

Primary antibody

Background

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462. AA range:1428-1477

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

200749

synonyms

Tuberin; TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein