TTI2 Antibody

Size

100ug

Clone Number

Aliases

C8orf41 antibody; CH041_HUMAN antibody; TELO2 interacting protein 2provided antibody; TTI2 antibody; Uncharacterized protein C8orf41 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6NXR4

Immunogen

Recombinant Human TELO2-interacting protein 2 protein (159-264AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:20-1:200

Background

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TTI2

Research Areas

Cell biology