TRPM2 Antibody

Size

100ul

Clone Number

Aliases

EREG 1 antibody; EREG1 antibody; Estrogen responsive element associated gene 1 antibody; Estrogen responsive element associated gene 1 protein antibody; Estrogen-responsive element-associated gene 1 protein antibody; KNP 3 antibody; KNP3 antibody; Long transient receptor potential channel 2 antibody; LTRPC 2 antibody; LTrpC-2 antibody; LTrpC2 antibody; MGC133383 antibody; NUDT9H antibody; NUDT9L1 antibody; putative Ca2+ channel protein antibody; putative Ca2+ channel protein antibody; Transient receptor potential cation channel subfamily M member 2 antibody; Transient receptor potential channel 7 antibody; TRPC 7 antibody; TrpC7 antibody; TRPM 2 antibody; Trpm2 antibody; TRPM2_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O94759

Immunogen

Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (1204-1503AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TRPM2

Research Areas

Cell biology; Metabolism; Signal transduction