TRPC6 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human TRPC6

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

102410

synonyms

TRPC6