TRIP10 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Cdc42 interacting protein 4 antibody; Cdc42 interaction protein 4 long isoform antibody; Cdc42-interacting protein 4 antibody; CG11341 antibody; CG15015 PA antibody; Cip 4 antibody; CIP4 antibody; CIP4_HUMAN antibody; DCIP4 antibody; hSTP antibody; Protein Felic antibody; Salt tolerant protein antibody; Salt tolerator antibody; STOT antibody; STP antibody; Thyroid hormone receptor interactor 10 antibody; Thyroid receptor interacting protein 10 antibody; Thyroid receptor-interacting protein 10 antibody; TR-interacting protein 10 antibody; TRIP 10 antibody; TRIP-10 antibody; trip10 antibody; Truncated Cdc42 interaction protein 4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15642

Immunogen

Recombinant Human Cdc42-interacting protein 4 protein (276-486AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TRIP10

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction