TRIM2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains| a RING| a B-box type 1 and a B-box type 2| and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human TRIM2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

81840

synonyms

TRIM2