TRI63 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

E3 ubiquitin-protein ligase TRIM63 ;EC 6.3.2.-;Iris RING finger protein;Muscle-specific RING finger protein 1;MuRF-1;MuRF1;RING finger protein 28;Striated muscle RING zinc finger protein