TRAF4 Antibody

Size

100ul

Clone Number

Aliases

CART 1 antibody; CART1 antibody; cysteine rich domain associated with ring and TRAF domain antibody; Cysteine rich domain associated with RING and Traf domains protein 1 antibody; Cysteine-rich domain associated with RING and Traf domains protein 1 antibody; Malignant 62 antibody; Metastatic lymph node gene 62 protein antibody; MLN 62 antibody; MLN62 antibody; RING finger protein 83 antibody; RNF 83 antibody; RNF83 antibody; TNF receptor associated factor 4 antibody; TNF receptor-associated factor 4 antibody; TRAF 4 antibody; Traf4 antibody; TRAF4_HUMAN antibody; tumor necrosis receptor-associated factor 4A antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BUZ4

Immunogen

Recombinant Human TNF receptor-associated factor 4 protein (251-470AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TRAF4

Research Areas

Cancer; Cell biology; Signal transduction