TPX2 Polyclonal Antibody

Ab type

Primary antibody

Background

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at Thr-288 and protects this residue against dephosphorylation.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DIL-2. AA range:301-350

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

85653

synonyms

TPX2; C20orf1; C20orf2; DIL2; IL 2; IL 2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein