TPRKB Antibody

Size

100ug

Clone Number

Aliases

CGI 121 antibody; My019 antibody; PRPK (p53 related protein kinase) binding protein antibody; PRPK-binding protein antibody; TP53RK binding protein antibody; TP53RK-binding protein antibody; Tprkb antibody; TPRKB_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y3C4

Immunogen

Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TPRKB

Research Areas

Signal transduction