TOPRS Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

E3 ubiquitin-protein ligase Topors ;EC 6.3.2.-;SUMO1-protein E3 ligase Topors;Topoisomerase I-binding RING finger protein;Topoisomerase I-binding arginine/serine-rich protein;Tumor suppressor