Topo III Alpha Polyclonal Antibody

Ab type

Primary antibody

Background

TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Topo IIIα . at AA range: 350-430

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

112372

synonyms

TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha