Topo I Polyclonal Antibody

Ab type

Primary antibody

Background

TOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Topo I.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

90726

synonyms

TOP1; DNA topoisomerase 1; DNA topoisomerase I