TNNC1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Troponin is a central regulatory protein of striated muscle contraction| and together with tropomyosin| is located on the actin filament. Troponin consists of 3 subunits: TnI| which is the inhibitor of actomyosin ATPase; TnT| which contains the binding site for tropomyosin; and TnC| the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI| thus allowing the interaction of actin with myosin| the hydrolysis of ATP| and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human TNNC1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

17710

synonyms

TNNC1