TNFRSF10A Antibody

Size

100ug

Clone Number

Aliases

Apo2 antibody; CD261 antibody; Cytotoxic TRAIL receptor antibody; Death receptor 4 antibody; DR4 antibody; NF related apoptosis-inducing ligand receptor 1 antibody; TNF receptor superfamily member 10a antibody; TNF-related apoptosis-inducing ligand receptor 1 antibody; TNFRSF10A antibody; TR10A_HUMAN antibody; TRAIL receptor 1 antibody; TRAIL-R1 antibody; TRAILR 1 antibody; TRAILR1 antibody; Tumor necrosis factor receptor superfamily member 10A antibody; Tumor necrosis factor receptor superfamily member 10a variant 2 antibody; Tumor necrosis factor receptor superfamily; member 10a antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00220

Immunogen

Recombinant Human Tumor necrosis factor receptor superfamily member 10A protein (263-468AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:100-1:500, IF:1:50-1:500, IP:1:200-1:2000

Background

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TNFRSF10A

Research Areas

Cardiovascular; Cell biology; Immunology