TNFAIP8 Antibody

Size

100ul

Clone Number

Aliases

GG2 1 antibody; Head and neck tumor and metastasis-related protein antibody; MDC-3.13 antibody; NDED antibody; NF-kappa-B-inducible DED-containing protein antibody; SCC S2 antibody; SCC-S2 antibody; SCCS2 antibody; TFIP8_HUMAN antibody; TNF alpha-induced protein 8 antibody; TNF induced protein antibody; TNF-induced protein GG2-1 antibody; TNFAIP 8 antibody; TNFAIP8 antibody; Tumor necrosis factor alpha induced protein 8 antibody; Tumor necrosis factor alpha-induced protein 8 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95379

Immunogen

Recombinant Human Tumor necrosis factor alpha-induced protein 8 protein (1-198AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TNFAIP8

Research Areas

Cancer; Cell biology; Immunology; Signal transduction