TNFAIP1 Antibody

Size

100ug

Clone Number

Aliases

TNFAIP1 antibody; BACURD2 antibody; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody; hBACURD2 antibody; BTB/POZ domain-containing protein TNFAIP1 antibody; Protein B12 antibody; Tumor necrosis factor antibody; alpha-induced protein 1 antibody; endothelial antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13829

Immunogen

Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 protein (233-316AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TNFAIP1

Research Areas

Signal transduction