TLR9 Antibody

Size

100ug

Clone Number

Aliases

CD 289 antibody; CD289 antibody; TLR 9 antibody; TLR9 antibody; TLR9_HUMAN antibody; Toll like receptor 9 antibody; Toll like receptor 9 isoform A precursor antibody; Toll like receptor 9 isoform B antibody; Toll-like receptor 9 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NR96

Immunogen

Recombinant Human Toll-like receptor 9 protein (425-563AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TLR9

Research Areas

Immunology; Signal transduction