TLR7 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

PRO285 antibody; TLR 7 antibody; Tlr7 antibody; TLR7_HUMAN antibody; Toll like receptor 7 antibody; Toll-like receptor 7 antibody; UNQ248 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NYK1

Immunogen

Recombinant Human Toll-like receptor 7 protein (899-1022AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TLR7

Research Areas

Epigenetics and Nuclear Signaling; Immunology; Signal transduction