TLE2 Polyclonal Antibody

Ab type

Primary antibody

Background

Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

79841

synonyms

TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2