tir Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody

Immunogen Species

Escherichia coli O157:H7 (strain TW14359 / EHEC)

UniProt ID

C6UYL8

Immunogen

Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)

Raised in

Rabbit

Species Reactivity

Escherichia coli O157:H7

Tested Applications

ELISA

Background

Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

tir

Research Areas

Others