TINF2 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

AW552114 antibody; D14Wsu146e antibody; DKCA3 antibody; MGC94711 antibody; TERF 1 (TRF 1) interacting nuclear factor 2 antibody; TERF 1 interacting nuclear factor 2 antibody; TERF1 (TRF1) interacting nuclear factor 2 antibody; TERF1 interacting nuclear factor 2 antibody; TERF1-interacting nuclear factor 2 antibody; Tin 2 antibody; TIN2 antibody; TINF 2 antibody; Tinf2 antibody; TINF2_HUMAN antibody; TRF 1 interacting nuclear factor 2 antibody; TRF1 interacting nuclear factor 2 antibody; TRF1-interacting nuclear protein 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BSI4

Immunogen

Recombinant Human TERF1-interacting nuclear factor 2 protein (210-451AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TINF2

Research Areas

Epigenetics and Nuclear Signaling