TIMM8A Antibody

Size

100ul

Clone Number

Aliases

DDP 1 antibody; DDP antibody; DDP1 antibody; Deafness dystonia protein 1 antibody; Deafness/dystonia peptide antibody; DFN 1 antibody; DFN1 antibody; MGC12262 antibody; Mitochondrial import inner membrane translocase subunit Tim8 A antibody; MTS antibody; TIM 8A antibody; TIM8 antibody; TIM8A antibody; TIM8A_HUMAN antibody; TIMM 8A antibody; timm8a antibody; Translocase of inner mitochondrial membrane 8 homolog A antibody; X linked deafness dystonia protein antibody; X-linked deafness dystonia protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O60220

Immunogen

Recombinant Human Mitochondrial import inner membrane translocase subunit Tim8 A protein (1-97AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TIMM8A

Research Areas

Neuroscience; Signal transduction