TH(Phospho Ser8) Polyclonal Antibody

Ab type

Primary antibody

Background

The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Reactivity

Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

58524

synonyms

Tyrosine 3-monooxygenase; TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH