TGIF1 Antibody

Size

100ug

Clone Number

Aliases

5' TG 3' interacting factor antibody; 5''-TG-3''-interacting factor 1 antibody; Homeobox protein TGIF antibody; Homeobox protein TGIF1 antibody; HPE4 antibody; MGC39747 antibody; MGC5066 antibody; TALE homeobox TG-interacting factor antibody; TG interacting factor isoform c antibody; TG-interacting factor antibody; TGFB induced factor antibody; TGFB-induced factor homeobox 1 antibody; TGIF1 antibody; TGIF1_HUMAN antibody; transforming growth factor-beta-induced factor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15583

Immunogen

Recombinant Human Homeobox protein TGIF1 protein (8-375AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TGIF1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Developmental biology; Signal transduction; Stem cells