ABCbiolab
SKU:ABCCS55240
TGFB1I1 Antibody
TGFB1I1 Antibody
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Size
100ug
Clone Number
Aliases
Androgen receptor coactivator 55 kDa protein antibody; Androgen receptor coactivator ARA55 antibody; Androgen receptor-associated protein of 55 kDa antibody; ARA55 antibody; Hic-5 antibody; Hydrogen peroxide-inducible clone 5 protein antibody; Tgfb1i1 antibody; TGFI1_HUMAN antibody; Transforming growth factor beta 1 induced transcript 1 antibody; Transforming growth factor beta-1-induced transcript 1 protein antibody; TSC 5 antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
O43294
Immunogen
Recombinant Human Transforming growth factor beta-1-induced transcript 1 protein (138-200AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200
Background
Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
TGFB1I1
Research Areas
Others
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