TGF beta 1 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation| differentiation and growth| and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human TGF β1 Polyclonal

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Transforming growth factor beta-1 ;TGF-beta-1 [Cleaved into: Latency-associated peptide ;LAP]; Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP;