TFAP2E Antibody

Size

100ug

Clone Number

Aliases

TFAP2ETranscription factor AP-2-epsilon antibody; AP2-epsilon antibody; Activating enhancer-binding protein 2-epsilon antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6VUC0

Immunogen

Recombinant Human Transcription factor AP-2-epsilon protein (66-175AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5\\\'-GCCNNNGGC-3\\\' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TFAP2E

Research Areas

Epigenetics and Nuclear Signaling