TFAP2B Antibody

Size

100ug

Clone Number

Aliases

Activating enhancer binding protein 2 beta antibody; Activating enhancer-binding protein 2-beta antibody; AP 2B antibody; AP2 B antibody; AP2-beta antibody; AP2B antibody; AP2B_HUMAN antibody; AP2beta antibody; MGC21381 antibody; OTTHUMP00000039925 antibody; PDA2 antibody; TFAP 2B antibody; Tfap2b antibody; Transcription factor AP 2 beta antibody; Transcription factor AP-2-beta antibody; Transcription factor AP2 beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92481

Immunogen

Recombinant Human Transcription factor AP-2-beta protein (111-208AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TFAP2B

Research Areas

Epigenetics and Nuclear Signaling; Cell biology