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ABCbiolab
SKU:ABCB05421
Tensin-1 Polyclonal Antibody
Tensin-1 Polyclonal Antibody
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Ab type
Primary antibody
Background
The protein encoded by TNS1 (tensin 1)localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reactivity
Human;Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human Tensin-1. AA range:1273-1322
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
185701
synonyms
TNS1; TNS; Tensin-1
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