TEL Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ETV6. AA range:371-420

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

53000

synonyms

Transcription factor ETV6; ETV6; TEL; TEL1; Transcription factor ETV6; ETS translocation variant 6; ETS-related protein Tel1; Tel