TCF3 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

AGM8 antibody; bHLHb21 antibody; Class B basic helix-loop-helix protein 21 antibody; E12 antibody; E2A antibody; E2A immunoglobulin enhancer binding factors E12/E47 antibody; E47 antibody; Helix loop helix protein HE47 antibody; Immunoglobulin enhancer-binding factor E12/E47 antibody; Immunoglobulin transcription factor 1 antibody; ITF1 antibody; Kappa-E2-binding factor antibody; MGC129647 antibody; MGC129648 antibody; Negative vitamin D response element binding protein antibody; NOL1-TCF3 fusion antibody; TCF-3 antibody; Tcf3 antibody; TFE2_HUMAN antibody; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody; Transcription factor 3 antibody; transcription factor 3 variant 3 antibody; Transcription factor E2-alpha antibody; Transcription factor ITF-1 antibody; VDIR antibody; VDR interacting repressor antibody; vitamin D receptor-interacting repressor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P15923

Immunogen

Recombinant Human Transcription factor E2-alpha protein (415-658AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5\\\'-CANNTG-3\\\'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TCF3

Research Areas

Epigenetics and Nuclear Signaling; Stem cells