TCEA3 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Rhabdomyosarcoma antigen MU RMS 40.22 antibody; Tcea3 antibody; TCEA3_HUMAN antibody; TFIIS antibody; TFIIS.H antibody; Transcription elongation factor A (SII) 3 antibody; Transcription elongation factor A protein 3 antibody; Transcription elongation factor A3 antibody; Transcription elongation factor S-II protein 3 antibody; Transcription elongation factor TFIIS.h antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75764

Immunogen

Recombinant Human Transcription elongation factor A protein 3 protein (79-169AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3\'-terminus.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TCEA3

Research Areas

Epigenetics and Nuclear Signaling